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Migraine Headache Prevention: When To Use Prophylactic Medications

Written and verified by Holly Hazen

The Goals of Migraine Headache Prevention Medications Are... @migrainesavvy #migrainerelief #stopmigraines #preventmigraine

You need to know when to consider taking daily migraine headache prevention? According to the Mayo Clinic’s website only 1 in 10 migraine sufferers take prophylactics, which I find quite alarming. So much needless pain and suffering.

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The statistics also show that only half of us are getting correctly diagnosed.

The Mayo Clinic also states that half of those of us who get migraines could benefit from taking preventative medications.

I don't mean to bog you down with statistics, but I want to point out that you may not be getting the help you need. And that the help could be available to you right now.

Having the right pain management strategy can drastically improve your life.

You Are A Candidate for Migraine Prevention Therapy If...

You may be considered a candidate for migraine headache prevention therapy if you have:

1. Two or more debilitating attacks a month,

2. Pain-relieving medications that aren't helping,

3. Poor or no response to acute drug treatment and your attacks continue, or

4. Migraine signs and symptoms include a prolonged aura or numbness and weakness.

5. A history of long-term, frequent, or excessive use of pain medications (analgesics) or acute medications that make your headaches worse or that have led to reduced responsiveness to other drug therapies.

The Goal of Migraine Headache Prevention Medications

The goal of preventive medications is to reduce the "frequency, severity and length of migraines and may increase the effectiveness of symptom-relieving medicines used during migraine attacks."

The American Migraine Foundation (AMF) says the "ultimate goals" of migraine prevention therapy are to:

1. Reduce frequency, severity, and duration of attacks;

2. Improve responsiveness to treatment of acute attacks;

3. Reduce level of disability;

4. Maintain cost of care for migraine treatments;

5. Reduce excessive or overuse of acute medications.

The Mayo Clinic also says that "in most cases, preventive medications don't eliminate headaches completely and some cause serious side effects." The AMF also says it's rare that preventive therapy completely eliminates migraine headaches.

If you find the right meds, and have had good results by remaining migraine-free for six months to a year, your doctor may recommend changes in the treatment plan to see if the migraines return. However, you may still need to find abortive medication that works safely with your preventive for acute attacks.

That's right - you will still need to take an abortive to stop an attack should the preventive not stop them sufficiently.

You may have to take both a preventive and an abortive to effectively manage your acute migraine attacks. 

Prophylactics Have to Be Taken Every Day

Prophylactics have to be taken every day to help prevent migraine attacks from occurring.

They are found to be most useful for people who have chronic, frequent, severe migraines or who also have other co-existing medical conditions that prevent them from taking any of the acute migraine medicines. They are not intended to be used to treat an acute attack.

Common drug classes for migraine prevention are: Beta blockers, calcium channel blockers, tricyclic antidepressants, and anticonvulsants.

It is important that preventive therapy be individualized and take into account the medications efficacy, potential adverse effects, the patient’s co-existing medical conditions and in most cases the associated drug costs.

Choosing preventative therapy can be a very complex process if you are taking other medications.

Other Ways to Prevent Migraine Headaches

Here are some natural ways to help you proactively prevent your migraine attacks:

  • Vitamins and supplements help minimize the causes of migraines and provide between migraine support. Migra-Eeze is great for aborting attacks for some of us too.
  • Biofeedback training is proven to help migraine pain and reduce future attacks.

More To Read


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How to be more migraine savvy right now...

Migraine Headache Prevention References:
1. Adelman J.U. and Adelman R.D. (2001) Current options for the prevention and treatment of migraine. Clinical Therapeutics 23(6) pp. 772-88, cited on U.S. National Library of Medicine – National Institutes of Health (NIH). Available at: Accessed June 21, 2016. 
2. American Migraine Foundation (AMF) Preventive Treatments. Available at: Accessed Aug 8, 2016. 
3. Migraine (updated June 17, 2016): Treatment and Drugs. Available at: Accessed June 21, 2016, Updated Mar. 9, 2019.